In this epic continuation, Dr. Kelson (Ralph Fiennes) finds himself in dire circumstances whose consequences could change the world as he knows it. Spike's (Alfie Williams) encounter with Jimmy Crystal (Jack O'Connell) becomes a nightmare from which he cannot escape. In the world of the Temple of Bones, the infected are no longer the greatest threat to survival—the inhumanity of the survivors may be stranger and more terrifying.